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2nd Zing Enzymes, Coenzymes and Metabolic Pathways Conference 2013

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New Frontiers in Enzymology: Enzyme Complexes and Regulation

This conference will highlight both fundamental and applied aspects of contemporary, state-of-the-art enzymology emphasizing enzyme complexes and the role of protein/protein interactions. In particular, the conference will offer sessions exploring new discoveries in metalloenzyme biochemistry, enzymology of nucleic acid replication and processing, multi-protein complex enzymatic systems, evolution of enzyme structure/function, and allosteric interactions in regulation, using a variety of methods such as mechanistic enzymology, enzyme dynamics, structural biology… The conference will feature lectures by many established leaders in the field, as well as emerging researchers, and offer a stimulating and collegial atmosphere for discussion, all in a beautiful Caribbean location.

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The Conference Chairs

Beatrice Golinelli-Pimpaneau
Centre National de la Recherche Scientifique


Elizabeth Komives
University of California, San Diego

Conference Sponsors


Abstract Submission Deadlines

Talk Deadline – 1st October 2013
Poster Deadline – 1st October 2013

Abstract Information Abstract Template Word Format Abstract Template .pdf Format

The Venue

Occidental Grand Xcaret
Playa del Carmen, Mexico.




Transfers & Tours

17 November 2013 – 21 November 2013

Located adjacent to the spectacular eco-archeological Xcaret Park in the heart of the Riviera Maya, the Occidental Grand Xcaret offers delegates the chance to exchange ideas and develop collaborations with colleagues in the tranquil setting of the Caribbean Sea.

Xcaret Park is Mexico’s most famous eco-archeological attraction. It is a beautiful place full of culture and nature where visitors can enjoy amazing aquatic activities, cultural attractions and shows. Xcaret Park is filled with the natural beauty of the Caribbean Sea and the magic of a thousand year- old civilization. It is the perfect place to experience the best of Mexico.

Hotel Features
11 Restaurants
5 swimming pools
10 Jacuzzis
Fully Equipped Gym
Beach Club
Organized sports and activities (pádel, tennis, mini golf and archery)

Venue Rating****
Nearest AirportCancún International Airport
Transfers & Tours View Details


Plenary Speakers


Gerald M Carlson
The University of Kansas

Quaternary Constraint Controls Both Catalytic Activities of the Hexadecameric Phosphorylase Kinase Complex


Eileen K Jaffe
Fox Chase Cancer Center

The morpheein model of protein allostery –  an anomaly or an overlooked generalization?


Nigel S Scrutton
Manchester Institute of Biotechnology

Protein dynamics underpinning catalysis in human cytochrome P450 reductase and related proteins


Josh Wand
University of Pennsylvania

The dark energy of proteins comes to light with an NMR relaxation based protein conformational entropy meter


Clay Clark
North Carolina State University

Conformational Ensembles in Caspases and Their Role in Cell Death


Gregory Grant
Washington University School of Medicine

 The Ins and Outs of Serine Metabolism: New Insights into the Regulation of Old Enzymes. 

Invited Speakers

SpeakerAffiliationPresentation Title
Cesar A. Ramirez-SarmientoUniversidad de ChileExpanded monomeric intermediate upon cold and heat unfolding of phosphofructokinase-2 from Escherichia coli
David BoehrThe Pennsylvania State UniversityDynamic amino acid networks in enzyme catalysis
Dirk Iwata-ReuylPortland State UniversityBiosynthesis of threonylcarbamoyl adenosine by a multi-protein complex
Dong WangUniversity of CaliforniaMolecular Basis of RNA Polymerase II Transcriptional Fidelity
Emily ParkerUniversity of CanterburyTurning enzymes on and off: Dynamic protein allostery
Jeffrey W KeillorUniversity of OttawaConformational changes of transglutaminase
Jianhua XingVirginia TechMathematical modeling fills the gap between molecular interactions and epigenetic dynamics
Penny J. Beuning Northeastern UniversitySpecificity of potentially mutagenic DNA polymerases for different types of DNA damage
Sylvie NesslerUniversity Paris SudMolecular mechanism of atypical bacterial tyrosine kinases involved in capsule biosynthesis
Zachary D. Nagel Massachusetts Institute of Technology Identification of a Long-range Protein Network that Modulates Active Site Dynamics in Extremophilic Alcohol Dehydrogenases
Helene Munier-LehmannInstitut PasteurAllosteric regulation of IMPDHs through their CBS domains
Ricardo O LouroITQB-UNLMind the gap: Unveiling the Redox Interactome across the Periplasm of Shewanella Oneidensis MR-1 that Sustains Extracellular Respiration

Contributing Speakers

Tadhg Begley
Texas A&M University

Coran Watanabe
Texas A&M University

Pablo Sobrado
Virginia Tech

Eugene G.Mueller
University of Louisville

William Bachovchin
Tufts University School of Medicine

Kirsten Wolthers
University of British Columbia

Saulius Klimasauskas
Vilnius University

Manfred Konrad
Max Planck Institute for Biophysical Chemistry

Todd Holyoak
University of Waterloo

Y. George Zheng
University of Georgia

Conference Programme

A copy of the conference programme is avaiable to view via the following link:Conference Programme

Conference Fees

StandardAccompanying Adult Accompanying Child (0-5 years)Accompanying Child (6-11 years)Extra Night AdultExtra Night Child (0-5 years)Extra Night Child (6-11 Years)
Day Pass $800
Payment DeadlineOct 30Oct 30Oct 30Oct 30Oct 30Oct 30Oct 30

Delegate Fees: Include conference registration and attendance, accommodation, all meals and drinks on a specially negotiated all-inclusive package and The Gala Night (including any accompanying persons).

Day Pass: includes conference registration and attendance, lunch and coffee breaks on conference days and The Gala Night. To register with a day pass please use the specified link below.

Accompanying Persons Fees: Include the same specially negotiated all-inclusive package as delegates excluding conference attendance.

Additional Night Fees: Prices are per person per night.

Conference Sponsors


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