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4th Zing Drug Discovery Conference 2014

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2nd International Conference on Global Challenges for New Drug Discovery Against Tropical Parasitic Diseases

Please Note – The Hotel is now full and we can only offer Day Passes for this Conference


The tropical parasitic diseases are responsible for staggering morbidity and millions of deaths every year, especially in the tropical regions of the word. Although incidences of these diseases are mostly centered in tropical regions the socioeconomic and public health impacts of tropical parasitic diseases are global. More then half of the world’s population is currently under the risk of being exposed to the infection with one or the other tropical disease pathogens. Emergence and spread of drug-resistant and more virulent strains of the parasites have further intensified the problem. Despite of the heavy burden on humanity the tropical parasitic diseases have been mostly ignored in relation to advances in modern drug discovery and only few new antipatasitic drugs have been developed during last several years.

Improved global attention with increasing funding opportunities through public and non-profit organizations as well as emergence of public-private partnerships for development of strategies to monitor, treat, control and eliminate neglected tropical parasitic diseases have generated unprecedented interests in new programs on discovery and development of drugs/vaccines. Significant increase in global business practices and leisure travel to the endemic counties require effective measures to protect the transient population from getting afflicted with the tropical parasitic diseases.

This conference shall focus on multidisciplinary efforts directed against control, treatments and elimination of neglected parasitic diseases namely, (a) Socioeconomic and public awareness programs in neglected tropical infectious diseases; (b) Monitoring, containment and treatment of drug resistant cases; (c) Translational research to evaluate new drugs and drug combinations (d) Molecular targets-based and structure-based medicinal chemistry approach to maintain healthy drug-discovery pipelines and (e) Opportunities to develop multidisciplinary programs and current funding opportunities.

IJPDDRIn conjunction with the conference, the International Journal for Parasitology: Drugs and Drug Resistance (IJP:DDR), an open access journal, will publish a special issue dedicated to research on drug discovery against parasitic diseases. Attendees are therefore encouraged to submit original scientific manuscripts in the subject area to the journal to be considered for publication in the special issue. All manuscripts will undergo peer-review and must meet the normal standards for publication in IJP:DDR.

The deadline for consideration of a submitted manuscript is May 1st, 2014, but authors are encouraged to submit earlier, so as to help speed the review process. It is anticipated that the special issue of IJP:DDR will be published in fall 2014. Submit my manuscript

Potential Speakers- Leading experts from academia, pharmaceutical companies, public-government agencies, non-profit agencies and private-public partnerships.

Target Audience- Researchers and students from Academic institutions, pharmaceutical companies with global health portfolio; Officials and policy makers from government agencies and non-profit organizations.

Register Now

Please Note – The Hotel is now full and we can only offer Day Passes for this Conference

Conference Programme

Conference Programme
Please Note: This Programme is liable to change and will be updated regularly. We strongly recommend periodically reviewing this document.

Conference Sponsors


The Conference Chairs

Babu L. Tekwani 2


Babu L. Tekwani
University of Mississippi

        • Principal Scientist in the National Center for Natural Products Research
        • Coordinator, UM/WRAIR Discovery Program
        • Professor of Pharmacology
peter myler


Peter Myler
Seattle Biomedical Research Institute

        • Full Professor, Seattle Biomedical Research Institute
        • Research Professor, Department of Global Health, Department of Medical Education and Biomedical Informatics, University of Washington

Abstract Submission Deadlines

Talk Consideration – 19th November 2013
Poster Deadline – 17th December 2013

Abstract Information Abstract Template Word Format Abstract Template .pdf Format

The Venue

Parador de Nerja
Nerja, Malaga. Spain

17th February 2014 – 20th February 2014

This contemporary Parador is situated on a cliff overlooking the beach and ocean, with a pleasant lawn complete with chaises and umbrellas where you can feel away from the madding-crowd below. You can choose to swim in the Parador’s swimming pool or take the private glass elevator/lift down to the beach. With bright and spacious common areas featuring works of art by well-known contemporary artists Bajola, Belén Comthe and Dario Basso; this property has a particularly pleasing ambiance and is the perfect location to absorb the scientific content of the conference and unwind during  free-time.


Transfers & Tours

Venue Rating ****
Nearest Airport Málaga Airport
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Plenary Speakers

Larry A. Walker

Larry Walker
University of Mississippi

The safety and efficacy of 8-aminoquinolines: new insights from metabolism and structure-activity considerations

Rosemary Rochford

Rosemary Rochford
SUNY Upstate Medical University

Use of humanized SCID mouse models for anti-malaria drug evaluation

Simon Croft

Simon Croft
London School of Hygiene and Tropical Medicine

Challenges And Opportunities For The Development Of New Treatments For Leishmaniasis

Steve Ward

Steve A Ward
Liverpool School of Tropical Medicine

A•WOL drug discovery – Hit identification and lead optimisation of novel compounds with efficacy against Wolbachia endosymbionts of filarial nematodes

R. Luise Krauth-Siegel

R. Luise Krauth-Siegel
University of Heidelberg

The Trypanothione System – Which opportunities does the Parasite-Specific Pathway Offer for a Target-Based Drug Development?

Invited Speakers

Speaker Affiliation Presentation Title
Manuel Fresno Universidad Autonoma de Madrid Immunotherapy‚ an Alternative Approach to Treat Neglected Protozoan Diseases
Pradeep Das Indian Council of Medical Research To Be Confirmed
Rafael Balana-Fouce  Universidad de Leon DNA Topoisomerase IB in Leishmania; A Pivotal Target for Drug Development
Sanjeev Krishna  St George’s University of London Artemisinin resistance: dogmas and antidogmas
Vicky Avery  Griffith University HTS Approaches in Parasitology:  Challenges and Successes
Hugo Cerecetto Universidad de la República – Uruguay Looking for New Anti-T. Cruzi Drugs: Surpassing the “Hit-To-Lead” Phase
Rentala Madhubala Jawaharlal Nehru University Aminoacyl tRNA synthetases and their paralogs from Leishmania: Novel anti-leishmanial drug targets
Zlatko Janeba Institute of Organic Chemistry and Biochemistry AS CR Potential Role of Acyclic Nucleoside Phosphonates in the Treatment of Malaria
Rosa M Reguera Universidad de León Fluorescent imaging in Leishmania investigation; a trend for new challenges
Thomas Kurz Heinrich-Heine-University IspC as target for antiplasmodial drug discovery: Synthesis‚ enantiomeric separation and structural biology of reverse fosmidomycin derivatives
Mercedes González Universidad de la República – Uruguay Getting insight on the mode of action of anti-T.cruzi agents: from metabolimic to death mechanism studies
Adam Renslo University of California Antimalarial Peroxides: Mechanistic Studies and Next-Generation Drug Delivery Systems
Achim Schnaufer  University of Edinburgh Mitochondrial Gene Expression as a Target for Novel and Existing Anti-Trypanosomatid Therapies
Amit Sharma International Centre for Genetic Engineering and Biotechnology Insights into Inhibitor Discovery against Malaria Parasite Proteins
Andrew Knox  Trinity College Dublin Putting African Sleeping Sickness to Bed – Rational and Drug Repositioning Approaches
David Wright  Vanderbilt University Effect of Antimalarials on Heme Speciation in the Malaria Parasite Plasmodium falciparum
Inigo Angulo Barturen GlaxoSmithKline New Paradigms to Use Animal Models as Drug Discovery Accelerators
Kiaran Kirk  The Australian National University Targeting ion transport in the malaria parasite with new-generation antimalarials
Manu De Rycker  University of Dundee Hit Discovery Approaches for Trypanosomatid Diseases
Robert T. Jacobs  Anacor Pharmaceuticals Inc. Antiparasitic Activities of Novel Boron Containing Heterocycles: Discovery and Development of New Treatments for Human African Trypanosomiasis‚ Malaria and Filariasis
Mahmoud A. ElSohly ElSohly Laboratories Inc From  pharmocognosy of Artemisia annua to targeted therapy with orally active artemisinin dimers
Sanjay A. Desai National Institute of Allergy & Infectious Diseases Targeting ion and nutrient uptake by erythrocytes infected with malaria parasites
Philippe Christen University of Geneva Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana
Dolores Gonzalez-Pacanowska Instituto de Parasitología y Biomedicina Carbohydrate-binding agents act as potent trypanocidals that elicit modifications in VSG glycosylation
David Waterson MMV Medicines for Malaria Venture’s Drug Discovery Portfolio
Hira Nakhasi US Food & Drug Administration Ufm1 mediated protein modification pathway as drug target in the human protozoan parasite Leishmania donovani

Contributing Speakers

Vicente Larraga – Spanish Research Council
Kevin Saliba – The Australian National University
Nicholas Malmquist – Pasteur Institute
Mitchell Avery – University of Mississippi
Laura Maria Sanz-Alonso – GSK

Conference Programme

Conference Programme
Please Note: This Programme is liable to change and will be updated regularly. We strongly recommend periodically reviewing this document.

Conference Fees

The Zing Student Grant

We are proud to introduce the Zing Student Grant which offers students the chance to attend the conference free of charge. To enter, simply register for a conference and submit your abstract for consideration. For more information, please follow the link The Zing Student Grant (T&C’s apply)

Standard Accompanying Adult Accompanying Child Extra Night Adult Extra Night Child
Conference Day Pass €750
Academic €1410 €660 €75 €115 €25
Industry €1410 €660 €75 €115 €25
Student €1200 €660 €75 €115 €25
Registration & Payment Deadline Jan 16 2014 Jan 16 2014 Jan 16 2014 Jan 16 2014 Jan 16 2014

Conference Day Pass : Price includes conference registration and attendance, lunches, coffee breaks and the Gala Night. This option does not include evening meals or accommodation.

Delegate Fees: Include conference registration and attendance, accommodation, all meals on a specially negotiated full-board package and The Gala Night (including any accompanying persons).

Accompanying Persons Fees: Include the same specially negotiated full-board package as delegates excluding conference attendance.

Group Discounts: Special discounts are offered for group bookings of 6 or more students from the SAME lab. Please contact us for more information

Additional Night Fees: Prices are per person per night on a Bed & Breakfast basis. Spaces are extremely limited so we encourage you to notify us immediately should you require additional nights at this venue

Children: Children aged 12 and above are regarded as adults by the hotel. Children under the age of 2 years stay free of charge.


Please Note: Your accommodation will not be reserved and conference registration is not confirmed until Zing Conferences Ltd have received full payment of all outstanding fees.


Conference Sponsors


Register Now

Please Note – The Hotel is now full and we can only offer Day Passes for this Conference

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