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Immune System for a Therapeutic Benefit

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Tailoring immune responses to therapeutic needs.

We are proud to announce the 1st Zing Immune System for a Therapeutic syringe-417786_640Benefit Conference will be taking place between the 30th September – 3rd October 2015 at the Parador de Oropesa in Spain.

The immune system has the ability to mount very precise immune responses without incurring damage to self. Its antibodies target extracellular antigens, and its thymus processed (T-) cells evolved to recognize intracellular antigens. This potential has been widely exploited for generation of vaccines, but more recently extended to creation of new therapies beneficial to autoimmune diseases, allergy, chronic inflammation, cancer, stem cell and organ transplantation, osteoporosis, blood dyscrasias, and infectious diseases, amongst others.

This symposium focuses on cutting edge developments in these areas of unmet medical need.

Conference Sponsors



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The Conference Chair

WaldmannHerman Waldmann
University of Oxford

Herman Waldmann is currently (since 1994) Professor of Pathology and Head of the Sir William Dunn School in Oxford. He qualified in medicine in 1971, and then began his scientific career in Cambridge where he studied mechanisms by which cells of the immune system could interact to mount immune responses. During this period he developed new methods of measuring the frequencies of cells specific for antigen. This early work led him to become interested in immunological tolerance and achieving tolerance for therapeutic purposes.

Soon after the discovery of monclonal atibodies Waldmann spent a short sabbatical with Milstein where he began to develop rat monoclonal antibodies to mouse and human lymphocytes. From 1980 he has been funded by an MRC Programme Grant to study mechanisms of transplantation tolerance and strategies to achieve this both experimentally and clincially. In 1989 the University conferred on him a personal chair “Kay Kendall Chair in Therapeutic Immunology”. In 1985 he published the first studies to show that short courses of CD4 antibody therapy could bring about long-term immunological tolerance to foreign proteins, and this work led on to the first demonstrations of transplantation tolerance resulting from short-tem antibody blockade.

His interest in establishing the rules by which antibodies kill cells came from a desire to maximize lysis where desirable, and to blockade function without lysis as part of tolersnce protocols. It was this work with CD52 antibodies that brought him and Winter together.

His mechanistic studies of tolerance uncovered a role for regulatory T-cells in “Infectious Tolerance”which was published in a seminal paper in Science in 1993. The strategies emerging from his laboratory since that time have been based on the use of therapeutic antibodies to enhance regulation over conventional T-cell immunity.

In order to apply antibodies clinically Waldmann developed the first academic antibody therapeutic manufacturing facility. He and his team were able to apply clinical grade antibodies in a wide range of probing therapeutic studies which enabled them to develop a series of humanized antibodies (CD52, CD3, CD4 and others) which have since been transferred to the pharmaceutical industry. His teams worjk since 1971 has resulted in more than 500 publications, the majority directed to therapeutic antibodies and their mechanisms of action.

These contributions have led to his election to the Royal Society in 1990, and the award of the Jose Carreras medal of the European Hematology Society in 2005, and a JDRF Excellence in Clinical Research Award in the same year. In 2007 he was awarded the Thomas E Starzl Prize in Surgery and Immunology and a Scrip Lifetime Achievement award. In 2008 he was awarded an honorary degree (ScD) from the University of Cambridge.


Talk Consideration Deadline: 27th August 2015……Poster Submission Deadline: 27th August 2015

For general abstract information or to download a copy of our abstract template please follow the links below.

info-Custom-2 Abstract Information……….Word-Custom Abstract Template Word Format……….pdf-Custom Abstract Template PDF Format

If you have already registered for this conference and now wish to submit your abstract or send a revised version, you can either Sign In to your account and add the abstract or Submit Your Abstract directly to us using the links below.

Sign In………. Submit Your Abstract

The Venue

Parador de Oropesa
Oropesa, Spain



30th September 2015 – 3rd October 2015

The Parador Oropesa is located in the beautiful Castillian countryside to the west of Madrid. Set in the former ancestral home of the Counts of Oropesa and located in the shadow of the Sierra de Gredos mountains, over the centuries, its Medieval cloisters and towers have accommodated aristocracy, bishops and soldiers.

There are two castles separated by an immense wall that is crowned by a magnificent machicolated parapet and an awesome tower. At one time the castle complex was controlled by Don Francisco de Toledo – Duke of Alba, and the Viceroy of Peru.  He and later lords added an extended set of palatial rooms and quarters to create what remains today.

The bedrooms are spacious with simple Castilian styled, dark wood furniture, with all rooms offer inspiring views – either to the castle tower, the Gredos plains, or the Gredos peaks. There are fine views from any table in the restaurant, with those located against the glass wall on the north side offering particularly stunning panoramic views.


Venue Rating****
Nearest AirportMadrid Barajas
TransfersClick Here


Plenary Speakers


Antonio Lanzavecchia
Institute for Research in Biomedicine
From broadly neutralizing antibodies to a new mechanism of diversification


Andrew Mellor
GRU Cancer Center
The Role of Tryptophan Catabolism in Inflammatory Disease Progression and Therapy: An overview


Ira Mellman
The mechanistic basis of cancer immunotherapy


Alasdair Coles
University of Cambridge
Advances in the treatment of Multiple Sclerosis


Zelig Eshhar
Weizmann Institute of Science
The CAR T-Cell Approach: From the Mouse Cage to the Patients’ Health


Gitta Stockinger
National Institute for Medical Research
Th17 cell plasticity- expanding the repertoire in health and disease

Invited Speakers

SallustoFederica Sallusto
Institute for Research in Biomedicine
Heterogeneity and Diversification of Human T-cell responses
BruggemanMarianne Brüggemann
Open Monoclonal Technology Inc.
Expression of human antibody repertoires in rodents from engineered IgH and IgL loci
chatenoud-150x150Lucienne Chatenoud
INSERM – Université Paris Descartes
Anti-CD3 antibodies in therapy
Silva-santos-150x150Bruno Silva-Santos
Instituto de Medicina Molecular
The role of gamma delta T-cells in health and disease
hollanderGeorg Holländer
University of Basel
Central tolerance induction: Cellular and molecular aspects
grucaLuís Graça
Instituto de Medicina Molecular
Heterogeneity in FoxP3 Regulatory T-cells
bach-CustomJean-François Bach
Necker Hospital
Hygiene Hypothesis and Autoimmune Diabetes
reisnerYair Reisner
Weizmann Institute of Science
Immune regulation in Metabolic Syndrome by Perforin-Positive Dendritic Cells
isaacsJohn Isaacs
Newcastle University
Rheumatoid Arthritis – from Palliation to Remission in 20 years
Sanchez-MadridFrancisco Sánchez Madrid
Autonomous University of Madrid
Leukocyte activation receptor CD69 and ligands: Immunoregulatory role in inflammatory processes.
de-fougerolles-CustomAntonin de Fougerolles
Nanobodies and their uses against single and multiple targets
betzAlex Betz
MRC Laboratory of Molecular Biology
Foxp3, an unconventional transcription factor with therapeutic potential

Contributing Speakers

Alex Chenchik
Cleo Goyvaerts
Vrije Universiteit Brussel
Karine Breckpot
Vrije Universiteit Brussel
Su Metcalfe
University of Cambridge
Hwajung Yi
Korea National Institue of Health

Conference Programme

programme-pic-e1436367393550A copy of the conference programme can be viewed by using the link below.
Please Note: This programme is subject to change. The programme will be updated regularly as information is received and we will always display the most current version here. We strongly recommend periodically reviewing this document.

Conference Programme

Conference Fees

We can offer 3 types of registration for the conference

  • An Event Pass without accommodation
    Provides full conference attendance whilst leaving you free to book your own accommodation.
  • An Event Pass with accommodation.
    This package provides full conference attendance and accommodation at the Parador Oropesa.
  • An Event Pass with shared accommodation.
    Share a room with another delegate at the venue to receive the best priced conference attendance and accomodation package.
Event Pass Only – No Accommodation

Event Pass

Standard Price €750
Standard Price valid from 1st July

Register Now

Event pass fees include

  • Conference registration
  • Welcome reception
  • Attendance to all scientific sessions
  • Conference Pack containing programme & abstract book
  • Wifi in conference room and guest rooms
  • Hot & cold buffet lunches
  • Evening meals on Days 1 & 2 including limited wine/beer/soft drinks
  • All coffee breaks during the conference
  • Poster session & refreshments
  • Ample time & opportunities for networking
  • On-site assistance from Zing staff available throughout the conference
  • Farewell Dinner Ticket

Event pass fees do not include

  • Accommodation at the conference venue
  • Breakfast

*Please Note: The Earlybird Rate of €620 was valid for those who registered and paid in full by 30th June 2015. Since 1st July, the Event Pass has reverted to the standard price of €750.

Event Pass With Accommodation Packages

Academic Price

Sharer Price
€900 €799

Register Now

Event pass and accommodation package fees include

  • Conference registration
  • Welcome reception
  • Attendance to all scientific sessions
  • Conference Pack containing programme & abstract book
  • Wifi in conference room and guest rooms
  • Hot & cold continental buffet breakfast
  • Hot & cold buffet lunches
  • Evening meals including limited wine/beer/soft drinks
  • Farewell Dinner including local entertainment
  • All coffee breaks during the conference
  • Poster Session & refreshments
  • 3 Free drink vouchers for selected drinks at the hotel bar
  • 50% discount on all subsequent drinks purchased at the hotel bar
  • Ample time & opportunities for networking
  • On-site assistance from Zing staff available throughout the conference

Accommodation Option
Academic Registrations have a private room. We offer the Sharer rate based on 2 persons sharing a room at the conference.

Please be aware if you book this package you will be sharing a room with another same sex attendee.

If you would like to nominate another attendee to share the room, please notify us of this fact in the ‘Special Requirements’ field of the registration form.

Please Note – Zing has exclusive use of the Parador Oropesa for the duration of the conferences and there are a limited amount of rooms available at the hotel. Until Zing Conferences receives full payment of your invoice, your room will not be reserved and will be allocated on a first-come first-served basis.

The reduced sharer rate of €799 was valid for those who registered and paid in full by 30th June 2015. Since 1st July, the rate has reverted to the standard price of €900. From 24th August, the €799 sharer price was reintroduced as a special offer.

We cannot offer any additional nights accommodation at the Parador before or after the conference dates. Should you require to stay extra nights, we can advise you on alternative accommodation in the local area. Please contact info@zingconferences.com for details

Alternate Accommodation

Here are a few alternative accommodation options available in the local area of Oropesa. Please use the links to view each property, the latest rates and reserve your accommodation.


Casa Rural La Posada


Casa Rural La Botica


La Hosteria de Oropesa



Please note: The owner of Casa Rural La Posada only speaks Spanish. Should you wish any information about the property or wish to make a booking, you may use our Spanish speaking colleagues to help. They can be contacted via the following email address zing@islandbridge-events.com

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