Nucleic Acids Meeting 2012
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| Chairs | David Lilley (University of Dundee) Wei Yang (NIDDK, National Institutes of Health) |
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| Date | Wednesday November 14 2012 - Sunday November 18 2012 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Synopsis | Nucleic acids - DNA and RNA - play the key informational role in the cell. But they are also structural, regulatory, and they can even behave like enzymes. The DNA in the nucleus is wrapped up in chromatin structure, yet it remains accessible to the transcription machinery and to repair proteins. Moreover its topology is manipulated by extraordinary enzymes. RNA undergoes a complex folding process that creates structures that can recognise and bind small molecules, and even accelerate chemical reactions by a million fold or more. RNA can control its own processing, catalyze protein synthesis and act as a key regulatory molecule in the cell. Understanding all these processes at the molecular level is the major theme of this conference. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Confirmed oral presentations |
Programme · Talk Titles
Plenary
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| Abstract submission |
Sorry, but all abstract deadlines have passed.
To secure your place at the conference, register now. |
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| See the 2010 programme | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Register now ( ) to secure your place. |
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Fees |
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Multiple attendance discount: 3 or more members from the same lab are eligible for a discount. Please contact us. Multiple conference discount: We can offer you a discount if you wish to attend multiple conferences. Please contact us. |
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Nucleic Acids meeting 2012 schedule
Confirmed oral presentations
Adam Roth (Yale University)
Searching for Novel Ribozymes
Adrian Ferre Damare (NIH)
Did the glmS ribozyme-riboswitch evolve from a coenzyme-independent self-cleaving RNA?
Ailong Ke (Cornell Univeristy)
The secretory proprotein convertase PC7: an anxiety-modulating proteinase
Alain Laederach (University of North Carolina)
SNP induced RNA structure change in human disease
Alastair Murchie (Fudan University)
Riboswitch Control of Aminoglycoside Antibiotic Resistance
Alicia Byrd (University of Arkansas for Medical Sciences)
Identification of residues in a DNA helicase that are dispensable for strand separation but necessary for protein displacement
Alison Hickman (NIH)
The three-dimensional structure of Hermes, an insect DNA transposase, complexed with transposon ends
Anita Jones (University of Edinburgh)
Using the Fluorescence Decay of 2-Aminopurine as a Probe of Duplex Unpairing
Antoine van Oijen (University of Groningen)
Single-molecule studies of DNA replication: from in vitro to in vivo
Brandt Eichman (Vanderbilt University)
Structural basis for replication fork regression and Holliday junction migration by DNA damage response protein SMARCAL1
Charles Bell (The Ohio State University)
Snapshots of E. coli Exonuclease I in complex with ssDNA suggest an inchworm mechanism for processive digestion
Chirlmin Joo (Delft University of Technology)
Single-Molecule Approach to MicroRNA Protein Complexes
Dagmar Klostermeier (University of Muenster)
Coordinated DNA- and nucleotide-driven conformational changes at the beginning of the catalytic cycle drive negative supercoiling by DNA gyrase
Dong Wang (UCSD)
Molecular Basis of RNA Polymerase II Transcriptional Fidelity
Emmanuel Skordalakes (The Wistar Institute, UPENN)
Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA
Gregory Bowman (Johns Hopkins University)
Decoupling nucleosome recognition from DNA binding dramatically alters the properties of the Chd1 chromatin remodeler
Guy Poirier (Laval University)
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Hideki Aihara (University of Minnesota)
Structural basis for TDP2 multifunctionality and recognition of 5'-phosphotyrosine adducts
Ishita Mukerji (Wesleyan University)
Structure of DNA Four-Way Junctions Modulated by Ions and Proteins
Jamie Williamson ( The Scripps Research Institute)
Dynamics of Bacterial Ribosome Assembly in Cells
Jana Kasparkova (Academy of Sciences of the Czech Republic, Institute of BiophysicsInstitute)
Thermodynamics of translesion synthesis across a major DNA adduct of antitumor oxaliplatin
Jane Grasby (University of Sheffield)
Unpair to repair or degrade-specific chemistry at duplex ends
John Pascal (Thomas Jefferson University)
Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1
John Tainer (The Scripps Research Institute)
Structural, biochemical, and mutational analyses of Mre11 and FEN nucleases in DNA replication and repair responses
Kiyoshi Mizuuchi (NIH)
ATP-driven transport of DNA via self-organized protein patterning on an artificial ?nucleoid? surface
Manju Hingorani (Wesleyan University)
MutS Dynamics on DNA During Mismatch Recognition and Repair Initiation
Marshall Stark (University of Glasgow)
Architecture of the intertwined synaptic intermediate in DNA site-specific recombination by Tn3 resolvase
Matthew Comstock (Michigan State University)
Simultaneous high-resolution optical trapping and single molecule fluorescence measurements of the UvrD helicase: DNA motor protein structure and function observed simultaneously.
Max Greenfeld (Stanford)
Exploration of a Simplified RNA Folding Landscape
Michael Stone (UC Santa Cruz)
Telomere DNA structure and folding probed by Integrated Fluorescence and Magnetic Tweezers (IFaM) Spectroscopy
Miguel Garcia-Diaz (Stony Brook University)
MTERF proteins and the regulation of mitochondrial gene expression
P. Shing Ho (Colorado State University)
Biological halogen bonds in DNA Holliday junctions
Petra Kuehrova (Palacky University Olomouc, Department of Physical Chemistry and RCPTM)
Folding and unfolding of UUCG and GAGA hairpin tetraloops based on replica exchange molecular dynamics
Phoebe Rice (The U. of Chicago)
Convergent and divergent evolution in DDE recombinases
Roger Woodgate (LGI/NICHD)
Mechanisms employed by Escherichia coli to prevent ribonucleotide incorporation into genomic DNA by pol V
Saba Valadkhan (Case Western Reserve University)
The modular nature of RNA can generate complex functions in long non-coding transcripts
Sarah Woodson (Johns Hopkins University)
RNA architecture and the cooperativity of RNA folding
Scott Bailey (Johns Hopkins)
The CRISPR/Cas system: an RNA based Immune System in Prokaryotes
Scott C. Blanchard (Weill Cornell Medical College of Cornell University)
Allosteric control of the ribosome by small-molecule antibiotics
Scott Williams (NIH)
Molecular mechanism of Topoisomerase2-DNA adduct reversal by Tyrosyl-DNA phosphodiesterase 2 (Tdp2)
Sethu Pitchiaya (University of Michigan)
Intracellular Single Molecule High Resolution Localization and Counting of microRNAs
Stephen Carr (Research Complex at Harwell)
A Molecular Mechanism for Holliday Junction Resolution
Stephen White (St. Jude Children's Research Hospital)
Phage T4 Helicase Dda: Engineered to Optimally Perform Strand Separation and Remove Barriers
Sua Myong (University of Illinois)
Single molecule study of protein-nucleic acid interaction
Teruya Nakamura (Kumamoto Univ.)
Visualization of oxidized nucleotide processing by E. coli MutT
Thomas Carell (Ludwig-Maximilians-Universitaet)
DNA Bases Beyond Watson and Crick
Thomas Steitz (HHMI, Yale University)
Understanding the structural bases of various factor functions in protein synthesis
Virginijus Siksnys (Vilnius University Institute of Biotechnology)
RNA-guided DNA cleavage by the Cas9-crRNA complex mediates CRISPR-encoded immunity
Wah Chiu (Baylor College of Medicine)
Cryo-EM of Nucleic Acids
Wendy Gilbert (MIT)
Transcript Leader Annotation and Insight into Genes' Translational Behavior
Yamuna Krishnan (National Centre for Biological Science, TIFR)
SimpHony: Simultaneous pH mapping Technology enabled by DNA nanomachines.
Zev Bryant (Stanford University)
Structural dynamics and mechanochemical coupling in DNA gyrase
Zhen Huang (Georgia State University)
High Fidelity of Nucleic Acid Base Pairs Derivatized with Selenium