Structure Based Drug Design Conference 2016
Structure-Based Drug Design (SBDD) has evolved a great deal over the past 30 years since the concept of the “Lock and Key” hypothesis was first reduced to practice in the HIV-1 protease field, leading to the rational design of a number of molecules that are at the forefront of effective therapy. Evolution of techniques such as x-ray crystallography, NMR and computational chemistry have enabled a more informed understanding of binding events, encouraging many groups to employ SBDD strategies to a wide range of drug-relevant targets.
Zing’s inaugural SBDD event will showcase many of the advances made in structural biology, fragment-based methodologies and computational chemistry, demonstrating how these have been used to enable drug discovery programmes in a range of drug target classes from enzymes, to more complex GPCR’s and PPI’s. The conference will also feature some of the emerging technologies in the field, which will serve as a glimpse into the future of drug discovery as SBDD becomes more diverse and unrestrained.
You will enjoy the opportunity to engage with many of the pace-setters in the SBDD field, leaving with fresh ideas and concepts that will help to continue to build success in your drug discovery efforts.
MedChemNet is a unique platform aiming to promote global collaboration between all members of this multidisciplinary field, enabling you to make the right connections. As well as access to further exclusive articles, regular news updates, engaging multimedia content and exclusive features, you can connect with peers and follow opinion leaders, while sharing your own insights through blogs and videos to help further the discussion.
We believe that medicinal chemistry is central to tackling modern healthcare challenges, and that increased discussion and sharing of ideas will help propel the field forward at an even faster rate, making a real difference to those in need.
Talk Consideration Deadline: 12th December 2015 Extended to 30th December 2015……..Poster Submission Deadline: 12th January 2016
For general abstract information or to download a copy of our abstract template please follow the links below.
If you have already registered for this conference and now wish to submit your abstract or send a revised version, you can either Sign In to your account and add the abstract or Submit Your Abstract directly to us using the links below.
The Conference Chairs
Beatson Institute for Cancer Research
Carlsbad, San Diego. USA.
Surrounded by natural beauty and tucked away in a secluded area of Carlsbad, California, sits Omni La Costa. Located 30 miles from the San Diego International Airport, Omni La Costa brings delegates to a unique destination that breaks away from the ordinary and provides an idyllic location to serve as a conference host.
With a privileged location offering spectacular views of the green terrain and of The Flower Fields at Carlsbad Ranch situated 5 miles away. The excellent cuisine served in the restaurants promises to satisfy even the most demanding of palates, while the lounge provides the perfect setting to continue networking over a drink in relaxed surroundings at the end of the day.
|Nearest Airport||San Diego Int’l|
|Transfers||Info & Bookings|
For airport transfers from San Diego airport to Omni La Costa Resort you can use the following link to book a transfer with Supershuttle. They offer a discounted rate for Zing Delegates booking shared rides, or you can book a private sedan for your transfer.
Should you prefer, you can call Supershuttle to make your booking on 1-800-blue-van and use code VZPJN to receive your discount .
Nanyang Technological University & Karolinska Institute
Biophysics in the cell – CETSA to guide drug discovery
Novartis Institutes for BioMedical Research, Inc.
Redefining Structure-Based Drug Design: From First Principles to Discovery
Allosteric binding sites on GPCRs – A new opportunity for Structure-Based Drug Design
Simplifying Complexity Using Fragments
University of California, San Francisco
Small-molecule inhibitors of protein-protein interactions: reflections and projections
Important Aspects of Fragment Screening Collection Design
Structure-based Drug Design of Selective BCL-XL Inhibitors
Second-harmonic generation (SHG) as a sensitive, real-time probe of protein structure
Discovery of potent and kinase-selective p21-activated kinase 1 (PAK1) inhibitors.
University of California, Riverside
Structure-based design of covalent inhibitors targeting protein-protein interactions (PPIs)
Exploitation of a Novel Binding Pocket in Lp-PLA2 Discovered Through X-Ray Fragment Screening
Discovery of Novel Orexin-1 Selective Antagonists using NMR-Guided Conformational Design
Starting small and staying small: A guiding principle for fragment library design, fragment optimization and structure-based drug design
Takeda California, Inc.
Structure Guided Design and Optimization of Selective Kinase Inhibitors from Fragment Starting
Binding site elucidation and structure guided design of novel macrocyclic IL-17A antagonists
Fragment Inspired Leads for Inhibition of RPA70N Protein-Protein Interactions
Structure Based Design of Novel IRAK4 Inhibitors
Discovery of Verubecestat (MK-8931): A BACE Inhibitor in Phase 3 Clinical Development for Alzheimer’s Disease
A disciplined approach to the design of a potent, selective MNK1/2 inhibitor
Bigfoot, the Loch Ness Monster, and Halogen Bonds: Separating Rumours from Reality in Molecular Design
The VEGFR2 drug axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation
Indiana University School of Medicine
Chemical Computing Group
Open Eye Scientific
Poster Highlight Presenters
University of Cambridge
Takeda California, Inc.
A copy of the conference programme can be viewed by using the link below.
Please Note: This programme is subject to change. The programme will be updated regularly as information is received and we will always display the most current version here. We strongly recommend periodically reviewing this document.
We can offer 3 types of registration for the conference. Please review the available options to select the most appropriate for you. If you have any questions regarding the registration options, please get in touch via firstname.lastname@example.org
- An Event Pass with private accommodation.
This package provides full conference attendance and private accommodation at the conference venue. Sold Out
When Registering select – Academic/Industry
- An Event Pass with shared accommodation.
Share a room with another delegate at the venue to receive the best priced conference attendance and accommodation package. Sold Out
When Registering select – Sharer
- An Event Pass without accommodation
Provides full conference attendance whilst leaving you free to make your own accommodation arrangements.
When Registering select – Event Pass
*Please Note: When you register with the Sharer, Academic or Industry option, we will not secure your room at that time. Until Zing Conferences receives full payment of your invoice, your room will not be reserved and places will be allocated on a first-come first-served basis. We have a limited number of rooms secured at the advertised rates.
Academic or Industry rates are for one person only to stay in the room. Should you wish additional guests (such as wife, husband or children) to stay in the room with you additional fees will be payable.
The Earlybird Rates are valid for those who register and pay in full by 16th Nov 2015. After this date, the fees will return to the standard prices
Prices are shown and payable in Dollars. Payments can be made by bank transfer or credit card payment. We can no longer accept payment by cheque.