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The Pathobiology of the Lysosome and Lysosomal Diseases Conference

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Abstracts | Speakers | Venue | Programme | Conference Fees | Alternate Accommodation | Register

7th – 10th July 2016

Inner_ear_pathology_in_MPS_IIIB_mice_at_30_wks-D-Custom-3We are proud to announce The Pathobiology of the Lysosome and Lysosomal Diseases Conference 2016 shall take place at Clare College, Cambridge, UK in July 2016

This conference will present an overview of recent progress in the understanding and management of lysosomal storage disorders. Internationally renowned scientists will cover subjects ranging from the basic biology and pathophysiology of this group of disorders to discussions of animal models, genetics, advancements in treatment, and pharmacoeconomic challenges posed by rare diseases in general and lysosomal disorders in particular.


Conference Sponsors


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Media Partner

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Genetics in Medicine is the official journal of the American College of Medical Genetics and Genomics with a mission to enhance the knowledge and practice of medical genetics and genomics. This peer-reviewed monthly journal offers an unprecedented forum for the presentation of innovative, clinically relevant papers in contemporary genetic medicine, including such areas as genomics, chromosome abnormalities, metabolic diseases, single gene disorders and health services/implementation research.


Abstracts

Talk Consideration Deadline: 7th May 2016…….Poster Submission Deadline: 7th June 2016

For general abstract information or to download a copy of our abstract template please use the link below. If you have already registered for this conference and now wish to submit your abstract or send a revised version, you can either Sign In to your account and add the abstract or Submit Your Abstract directly to us using the links below.

We will not accept any abstract submissions from people who are not registered for the conference they are submitting the abstract for.
Register first – then submit your abstract.


The Conference Chairs

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Joe T.R. Clarke
University of Toronto

Dr. Clarke is a Professor of Pediatrics at the University of Toronto. In 1983, he joined the staff of The Hospital for Sick Children as an associate professor in pediatrics of the University of Toronto. He was, for 11 years, Head of the Division of Clinical Genetics of The Hospital for Sick Children. When the Genetic Metabolic Diseases Program was established he become the Director of the Department, a position which he held until 2006. He is currently a Senior Associate Scientist in the Research Institute of The Hospital for Sick Children. He is also Director of Postgraduate Education in Medical Genetics at the University of Toronto. He chairs the Ontario Advisory Committee on Newborn and Childhood Screening and is a member of the Ontario Advisory Committee on Genetics….Read more

Pastores

Gregory M. Pastores
Univeristy College Dublin

Gregory M. Pastores MD is Clinical Professor (Genetics), University College Dublin, Ireland, and Consultant with the Adult Metabolic Service/Department of Medicine/National Centre for Inherited Metabolic Disorders at the Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.

A graduate of the University of Sto. Tomas in Manila (1983), he trained in Pediatrics and Genetics at the Mount Sinai Medical Center in New York (1989) and at the Mayo Clinic in Minnesota (1991). While at Mount Sinai….Read more


The Venue

Clare College
Cambridge, England.

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Zing Conferences CIC is an organisation which is contracting Clare College for the use of facilities, but which otherwise has no connection or association with Clare College or the University of Cambridge.

7th – 10th July 2016

The city of Cambridge is a university city and the county town of Cambridgeshire, England which lies in East Anglia, on the River Cam, about 50 miles (80 km) north of London. Situated just 42miles from Luton Airport, 31 miles from Stansted Airport and 74 miles from Heathrow Airport.
Today, Cambridge is at the heart of the high-technology centre known as Silicon Fen and is home to the Cambridge Biomedical Campus, one of the largest biomedical research clusters in the world.
Founded in 1326 Clare College is the second oldest College in the University and resides in beautiful, riverside grounds and the beautiful Fellows Gardens to visit, spanning both sides of the River Cam running between the Old Schools (the administrative centre of the University) and the University Library.
The award winning conference room of the Gillespie Centre opened in January 2009. The light, airy design and flexible meeting rooms offer all the ingredients to host a memorable conference. The Centre, built to the highest standards of sustainability, uses solar thermal panels and a ground source heat pump for efficient heating and cooling.
All the on-site bedrooms are equipped with wired internet access, while the restaurants offer a wide variety of fresh, local produce with selections to tempt even the most refined palette.
We are sure you will agree, Clare College shall provide a magnificent setting for what will be a stimulating, enlightening and thought-provoking conference.

Nearest Airports
Cambridge Airport4 miles
Stansted30 miles
Luton39 miles
London City56 miles
Heathrow70 miles
Gatwick94 miles

Local Climate

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The United Kingdom is famous for its unpredictable weather, yet Cambridge and the surrounding areas benefit from some of the warmest and driest conditions in the country.

During the conference dates, Cambridge is usually bright and sunny with temperatures between 18° – 25° and a moderate risk of showers. We would recommend using the BBC forecast link to view the expected weather.


Plenary Speakers

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Fran Platt
University of Oxford
Dysfunction of the Niemann-Pick type C disease pathway in multiple human diseases

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Andrea Ballabio
The Telethon Institute of Genetics and Medicine (TIGEM)
The Awesome Lysosome

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Timothy M Cox
University of Cambridge
Lysosomes : descriptive medicine and emerging therapeutic science

Gruenberg

Jean Gruenberg
University of Geneva
Endosomal lipids in trafficking and signaling

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Gillian Griffiths
Cambridge Institute for Medical Research
The secrets of secretory lysosomes

Jaattela

Marja Jäättelä
Danish Cancer Society Research Center
Control of lysosomal stability and autophagosome maturation by sphingomyelin metabolism: opportunities for therapeutic intervention

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Ralph A. Nixon
Nathan S. Kline Institute for Psychiatric Research
Dysregulation of Lysosomal pH and Calcium Signaling: Emerging Factors in Neurodegenerative Disease


Invited Speakers

Futerman-CustomTony Futerman
Weizmann Institute of Science
Pathological pathways in neuronal forms of Gaucher disease.
Schroeder-CustomBernd Schröder
University of Kiel
Emerging function of the lysosomal membrane – more than just a barrier for lysosomal hydrolases
Nick-PlattNick Platt
Oxford University
Innate Immune Dysfunction in Lysosomal Storage Diseases
SpiegelSarah Spiegel
Virginia Commonwealth University
The active phosphorylated form of FTY720 is a HDAC inhibitor that Increases NPC1 and NPC2 Expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.
DAzzoAlessandra d’Azzo
St. Jude Children’s Research Hospital
Pathophysiology of Lysosomal Exocytosis: Do Not Tilt the Balance
HughesDerralynn Hughes
Royal Free & University College Medical School
LSD and malignancy
davidsonBeverly Davidson
University of Iowa
Old Tools and New Tricks
luzioPaul Luzio
Cambridge Institute for Medical Research
The dynamics of endolysosomes and the lysosome regeneration cycle
Biffi-CustomAlessandra Biffi
San Raffaele Telethon Institute for Gene Therapy

Contributing Speakers

Carlos Enrich
University of Barcelona
Abhinav Diwan
Washington University in St. Louis
Eric Hewitt
University of Leeds
Carlos R. Morales
McGill University
Fenghua Hu
Cornell University
Thomas Kirkegaard Jensen
Orphazyme
Arun Kumar Tharkeshwar
VIB-KU Leuven
Otilia V. Vieira
Universidade Nova de Lisboa
Janet Deane
University of Cambridge
Xianping Dong
Dalhousie University
Heather Gray-Edwards
Auburn University
Doug Brooks
University of South Australia
Anna Lisa Gündner
Roche Switzerland
Giuseppe Cammarata
IBIM CNR
Karin Öllinger
Linköping University
Isabella Azario
University of Milano-Bicocca
Xuesong Chen
University of North Dakota
Allison Bradbury
University of Pennsylvania
Jonathan Martinez-Fabregas
University of Dundee
Begoña Cachón-González
University of Cambridge
Gwen Gunn
University of Alabama at Birmingham
Douglas Martin
Auburn University
Debasish Sinha
The Johns Hopkins University School of Medicine
Thomas Vaccari
The Firc Institute of Molecular Oncology

Conference Programme

programme-pic-e1436367393550A copy of the conference programme can be viewed by using the link below.
Please Note: This programme is subject to change. The programme will be updated regularly as information is received and we will always display the most current version here. We strongly recommend periodically reviewing this document.

Conference Programme


Conference Fees

We can offer 3 types of registration for the conference. Please review the available options to select the most appropriate for you. If you have any questions regarding the registration options, please get in touch via info@zingconferences.com

Please Note – We have now sold out of rooms at Clare College. The registration options including accommodation are therefore no longer available. You can still register with an Event Pass and secure your own accommodation in Cambridge for the conference. Nearby options are listed in the Alternate Accommodation section below


All prices are shown and payable in Sterling (£) and are exclusive of VAT at 20%. Payments can be made by bank transfer or credit card payment. Unfortunately, we can no longer accept payment by cheque.


An Event Pass with private accommodation.
This package provides full conference attendance and private accommodation at the conference venue.

When Registering select – Academic/Industry


Academic/Industry Option
Earlybird Price £999* SOLD OUT
Earlybird Price valid until 31st March ’16
Standard Price £1100 SOLD OUT
Standard Price valid from 1st April ’16


Fees include
○ Conference registration
○ Private accommodation at Clare College
○ Welcome reception
○ Attendance to all scientific sessions
○ Conference Pack containing programme & abstract collection
○ Wifi in conference room and guest rooms
○ Breakfasts
○ Buffet lunches (including last day)
○ Evening meals including limited wine/beer/soft drinks
○ Farewell Dinner including limited wine/beer/soft drinks
○ All coffee breaks during the conference
○ Poster Session & refreshments
○ Ample time & opportunities for networking
○ On-site assistance from Zing staff available throughout the conference


Accommodation Nights – 7th, 8th & 9th July


An Event Pass with shared accommodation.
Share a room with another delegate at the venue to receive the best priced conference attendance and accommodation package.

When Registering select – Sharer………..


Sharer Option
Earlybird Price£800* SOLD OUT
Earlybird Price valid until 31st March ’16
Standard Price £899 SOLD OUT
Standard Price valid from 1st April ’16


Fees include
○ Conference registration
○ Shared accommodation at Clare College
○ Welcome reception
○ Attendance to all scientific sessions
○ Conference Pack containing programme & abstract collection
○ Wifi in conference room and guest rooms
○ Breakfasts
○ Buffet lunches (including last day)
○ Evening meals including limited wine/beer/soft drinks
○ Farewell Dinner including limited wine/beer/soft drinks
○ All coffee breaks during the conference
○ Poster Session & refreshments
○ Ample time & opportunities for networking
○ On-site assistance from Zing staff available throughout the conference


Accommodation Nights – 7th, 8th & 9th July


An Event Pass without accommodation
Provides full conference attendance whilst leaving you free to make your own accommodation arrangements.……..

When Registering select – Event Pass……..


Event Pass Option
Earlybird Price £699*
Earlybird Price valid until 31st March ’16
Standard Price £775
Standard Price valid from 1st April ’16


Fees include
○ Conference registration
○ Welcome reception
○ Attendance to all scientific sessions
○ Conference Pack containing programme & abstract collection
○ Wifi in conference room
○ Buffet lunches including the last day
○ Evening meals including limited wine/beer/soft drinks
○ Farewell Dinner including limited wine/beer/soft drinks
○ All coffee breaks during the conference
○ Poster Session & refreshments
○ Ample time & opportunities for networking
○ On-site assistance from Zing staff available throughout the conference

.
.


Accommodation & Breakfast Not Included


All prices are shown and payable in Sterling (£) and are exclusive of VAT at 20%. Payments can be made by bank transfer or credit card payment. Unfortunately, we can no longer accept payment by cheque.

*Please Note: When you register with the Sharer, Academic or Industry option, we will not secure your room at that time. Until Zing Conferences receives full payment of your invoice, your room will not be reserved and places will be allocated on a first-come first-served basis.. We have a limited number of rooms secured at the advertised rates.

Academic or Industry rates are for the registered delegate only to stay in the room. Should you wish additional guests (such as wife or husband) to stay in the room with you, additional fees will be payable.

Due to restrictions imposed by the venue, children under the age of 16 cannot stay at Clare College

Additional Nights: No extra nights can be added to this accommodation. Should you require to stay additional nights pre or post conference, alternative accommodation would have to be sourced.

The Earlybird Rates are valid for those who register and pay the fees in full by 31st March 2016. After this date, the fees will return to the standard prices. Paying the deposit does not entitle you to Earlybird prices after this deadline has passed.


Alternate Accommodation

If you are registering with the Academic/Industry or Sharer option, accommodation at Clare College is included in the fee. Should you be registering with the Event Pass without accommodation option you will need to source your own accommodation for your stay, below are some options nearby.

Hilton-DoubleTree
Hilton DoubleTree~10 minute walk to Clare College
Hilton-City-Centre
Hilton Cambridge City Centre~8 minute walk to Clare College
Acorn
Acorn Guest House~12 minute walk to Clare College
LanternOutside
Lantern Guest House~12 minute walk to Clare College

Arundel-Hotel-CustomArundel House Hotel can offer delegates staying 7 – 10th July a 10% discount on their standard price. Please mention you are a Zing delegate when making your booking to receive this discount.

Arundel House Hotel Bookings & Info


Register

Register Now


Lysosome